Problems of allergic nasal diseases. Treatment for aspirin asthma and nasal polyps.
نویسندگان
چکیده
منابع مشابه
Diagnostic Utility of Urinary LTE4 in Asthma, Allergic Rhinitis, Chronic Rhinosinusitis, Nasal Polyps, and Aspirin Sensitivity.
BACKGROUND Urinary leukotriene E4 (LTE4) is a well-validated marker of the cysteinyl leukotriene pathway, and LTE4 elevation has been described in conditions such as asthma, aspirin sensitivity, and chronic rhinosinusitis (CRS). There have been a number of reports investigating the role of spot urine LTE4 to predict aspirin sensitivity; however, variability in urinary LTE4 may affect the accura...
متن کاملOral and Nasal Steroids for Nasal Polyps
Introduction: Chronic rhinosinusitis (CRS) with nasal polyps is a common form of the disorder with distinct immunopathology and significant impact on the healthrelated quality of life of patients. Several treatment options—depending on the clinical course and severity of the disease—have been recommended, from medical therapy with oral or topical corticosteroids to various methods of surgical m...
متن کاملEvidence for interleukin-5 in nasal polyps in aspirin-induced asthma
Aspirin-induced asthma is often accompanied by nasal polyps, in which tissue eosinophils are abundant and activated. However, the mechanism of eosinophil infiltration remains unknown. We encountered two aspirin-induced asthma patients with nasal polyps and investigated eosinophil infiltration into nasal polyp tissue. Eosinophil chemotactic activity of extracts from the nasal polyp was elevated ...
متن کاملGene expression profiling of nasal polyps associated with chronic sinusitis and aspirin-sensitive asthma.
OBJECTIVE To identify genes whose expression is most characteristic of chronic rhinosinusitis and aspirin-sensitive asthma through genome-wide transcriptional profiling of nasal polyp tissue. STUDY DESIGN Prospective, controlled study conducted at a tertiary care institution. METHODS Thirty genome-wide expression microarrays were used to compare nasal polyp tissue from patients with chronic...
متن کاملGene-expression signatures of nasal polyps associated with chronic rhinosinusitis and aspirin-sensitive asthma.
PURPOSE OF REVIEW The purpose of this review is to highlight recent advances in gene-expression profiling of nasal polyps in patients with chronic rhinosinusitis and aspirin-sensitive asthma. RECENT FINDINGS Gene-expression profiling has allowed simultaneous interrogation of thousands of genes, including the entire genome, to better understand distinct biological and clinical phenotypes assoc...
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ژورنال
عنوان ژورنال: Practica Oto-Rhino-Laryngologica
سال: 1998
ISSN: 1884-4545,0032-6313
DOI: 10.5631/jibirin.91.432